Strategies for prevention and treatment of SARS-COV-2 infection in patients with chronic kidney disease: Literature review

Abstract

COVID-19 has proven to be particularly aggressive in patients with chronic kidney disease (CKD). The lower immune response rate and the greater susceptibility to progress to severe forms of the disease have contributed to this phenomenon, which has persisted in the post-vaccination era of the pandemic. Paradoxically, CKD has been excluded from most clinical trials of the main therapeutic tools developed against SARS-CoV-2. However, experience in the use of these drugs has been accumulating in different stages of CKD, supporting their use with guarantees of efficacy and safety. The objective of this review is to gather all treatment indications for COVID-19 in the different phases of the disease, tailored to CKD in its various stages, including renal replacement therapy.

Keywords: COVID-19 prophylaxis; COVID-19 treatment; Chronic kidney disease; Enfermedad renal crónica; Immunocompromised patient; Paciente inmunodeprimido; Profilaxis de la COVID-19; Tratamiento de la COVID-19.