Acute kidney injury after robot-assisted laparoscopic prostatectomy: A meta-analysis

Abstract

Background: We investigated the rates of acute kidney injury (AKI) post robot-assisted laparoscopic prostatectomy (RALP).

Methods: A comprehensive search was conducted to identify studies that reported the rates of AKI post-RALP. A random effects model was used, and the pooled rates of AKI were calculated.

Results: We identified 10 studies with 60,937 patients to be included. The mean age was 65.1 years. The mean anaesthesia time was 234.3 min (95% CI: 177.8-290.9). The mean operation time was 212.2 min (95% CI: 188.7-235.6). The mean estimated blood loss was 314.1 mL (95% CI: 153-475.3). The mean intraoperative IV fluids administered were 1985 mL (95% CI: 1516.3-2453.7). The pooled rate of AKI post RALP was 7.2% (95% CI 19-23.9).

Conclusions: The rates of AKI after RALP are significant. Further studies are needed to detect the risk factors for AKI and to determine the rates of chronic kidney disease post-RALP.

Keywords: acute kidney injury; pneumoperitoneum; prostate cancer; robot assisted laparoscopic radical prostatectomy.