Adenoid Cystic Cancer of the Lacrimal Gland: Management Aspects and Treatment Outcomes

Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):2158-2161. doi: 10.1007/s12070-023-04426-5. Epub 2023 Dec 21.

Abstract

Adenoid cystic carcinoma (ACC) of the lacrimal gland is the most common malignant epithelial tumor of the lacrimal gland. The biological behavior of these tumors is characterized by a slow growth with frequent nerve invasion but rare invasion of the neck nodes. Local extension intracranially with bone erosions is seen in locally advanced tumors. Distant metastasis to lungs bone and liver are commonly reported. Treatments using surgery and radiotherapy are generally preferred for adequate tumor control. However there is still no consensus on the best treatment approach.

Supplementary information: The online version contains supplementary material available at 10.1007/s12070-023-04426-5.

Keywords: Carcinoma; Lacrimal gland; Radiotherapy; Surgery.