Sedum aizoon L.: a review of its history, traditional uses, nutritional value, botany, phytochemistry, pharmacology, toxicology, and quality control

Front Pharmacol. 2024 Mar 14:15:1349032. doi: 10.3389/fphar.2024.1349032. eCollection 2024.

Abstract

In China, Russia, Mongolia, Japan, North Korea, and Mexico, Sedum aizoon L. (S. aizoon) is used as an edible plant. Up to now, over 234 metabolites, including phenolic acids, flavonoids, triterpenes, phytosterols, and alkaloids, among others, have been identified. In addition to its antioxidant, anti-inflammatory, anti-fatigue, antimicrobial, anti-cancer, and hemostatic activities, S. aizoon is used for the treatment of cardiovascular disease. This paper provides an overview of the history, botany, nutritional value, traditional use, phytochemistry, pharmacology, toxicology, and quality control of S. aizoon.

Keywords: Sedum aizoon L.; active metabolites; hemostatic activity; pharmacological activities; quality control.

Publication types

  • Review

Grants and funding

The authors declare that financial support was received for the research, authorship, and/or publication of this article. This research was carried out with the support of the Natural Science Foundation of Hubei Provincial Department of Education, grant number B2020104, the Innovation and Entrepreneurship Training Program for college students of Hubei University of Medicine, grant number X202110929016, and Hubei Key Laboratory of Wudang Local Chinese Medicine Research (Hubei University of Medicine), grant number WDCM2023025.