Changes in Stress Urinary Incontinence Symptoms after Pelvic Organ Prolapse Surgery: a Nationwide Cohort Study (FINPOP)

Int Urogynecol J. 2024 Apr;35(4):909-919. doi: 10.1007/s00192-024-05760-0. Epub 2024 Mar 28.

Abstract

Introduction and hypothesis: Various strategies are employed to manage stress urinary incontinence (SUI) during pelvic organ prolapse (POP) surgery. This study was aimed at facilitating shared decision-making by evaluating SUI symptom changes, staged SUI procedures, and their prognostic factors following POP surgery without concomitant SUI intervention.

Methods: We analyzed 2,677 POP surgeries from a population-based observational cohort, excluding patients with prior SUI surgery. The outcome measures were subjective SUI utilizing the Pelvic Floor Distress Inventory-20 questionnaire and number of subsequent SUI procedures. Multivariable linear models were applied to identify predictors of persistent SUI, procedures for persistent SUI, and de novo SUI. The primary assessment occurred at the 2-year follow-up.

Results: At baseline, 50% (1,329 out of 2,677) experienced SUI; 35% (354 out of 1,005) resolved, an additional 14% (140 out 1,005) improved, and 5.1% (67 out of 1,308) underwent a procedure for persistent SUI. De novo SUI symptoms developed in 20% (218 out of 1,087), with 3.2% (35 out of 1,087) reporting bothersome symptoms; 0.8% (11 out of 1,347) underwent a procedure for de novo SUI. High baseline symptom severity increased the risk of persistent SUI (adjusted odds ratio [aOR] 2.04, 95% confidence interval [CI] 1.65-2.53), whereas advanced preoperative apical prolapse decreased the risk (aOR 0.89, 95% CI 0.85-0.93). De novo SUI was more common with advancing age (aOR 1.03, 95% CI 1.01-1.05), baseline urgency urinary incontinence (aOR 1.21, 95% CI 1.06-1.38), and after transvaginal mesh surgery (aOR 1.93, 95% CI 1.24-3.00). It was not dependent on the compartment or preoperative degree of prolapse.

Conclusions: In a pragmatic setting, POP surgery results in a low rate of subsequent SUI procedures.

Keywords: De novo stress urinary incontinence; Pelvic organ prolapse; Pelvic organ prolapse surgery; Prognostic factor; Stress urinary incontinence.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Cohort Studies
  • Female
  • Gynecologic Surgical Procedures / adverse effects
  • Gynecologic Surgical Procedures / statistics & numerical data
  • Humans
  • Middle Aged
  • Pelvic Organ Prolapse* / surgery
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Surveys and Questionnaires
  • Treatment Outcome
  • Urinary Incontinence, Stress* / etiology
  • Urinary Incontinence, Stress* / surgery