Exploring the photocatalytic and photodynamic effects of BODIPY-linked titanium dioxide nanoparticles

Seda Demirel Topel

doi:10.55730/1300-0527.3623

Exploring the photocatalytic and photodynamic effects of BODIPY-linked titanium dioxide nanoparticles

Turk J Chem. 2023 Sep 30;47(6):1407-1419. doi: 10.55730/1300-0527.3623. eCollection 2023.

Author

Seda Demirel Topel¹

Affiliation

¹ Department of Electrical-Electronics Engineering, Faculty of Engineering and Natural Sciences, Antalya Bilim University, Antalya, Turkiye.

Abstract

This study aimed to investigate the photocatalytic and photodynamic actions of a 2,6-diiodinated-BODIPY (2,6-diI₂-Bod) photosensitizer (PS) covalently linked to TiO₂ nanoparticles (NPs). The TiO₂ NPs were synthesized utilizing the hydrothermal technique, yielding an average particle size of 4-5 nm as ascertained by transmission electron microscopy and 6.4 nm as determined by dynamic light scattering measurements. The integration of the nonsoluble Bod PS to TiO₂ NPs provided increased dispersibility in physiological media, making it more applicable to photodynamic therapy applications. Bod-TiO₂ NPs exhibited moderate efficiency of 56.9% in singlet oxygen generation. Additionally, the photocatalytic behavior of the TiO₂ NPs was evaluated using methylene blue and 83.8% photodegradation efficiency was observed. The loading efficiency and loading content of the Bod PS were found to be 90.8% and 54.5%, respectively. These results suggest that Bod-TiO₂ NPs possess higher dispersibility in aqueous solutions, moderate photocatalytic activity, and potential for photodynamic therapy applications.

Keywords: BODIPY; Titanium dioxide; photocatalyst; photodynamic therapy; photosensitizer.