Diffuse Large B-cell Lymphoma of the Ovaries Presenting With a Paraneoplastic Sclerotic Skin Lesion

Cureus. 2024 Feb 26;16(2):e54974. doi: 10.7759/cureus.54974. eCollection 2024 Feb.

Abstract

Paraneoplastic presentations are often the initial presenting symptom of a malignant process. A 15-year-old female presented with a progressively growing, sclerotic lesion of the neck restricting the range of motion. She was found to have bilateral ovarian tumors that proved to be diffuse large B-cell lymphoma (DLBCL). After starting cyclophosphamide, vincristine, and prednisone (COP), she had a rapid and complete resolution of the sclerotic lesion, as well as a favorable response to the neoplastic process. In this report, we present a very rare case of extranodal lymphoma associated with a paraneoplastic skin lesion.

Keywords: dlbcl; ovarian lymphoma; ovarian tumor; paraneoplastic syndromes; rare presentations; scleroderma.

Publication types

  • Case Reports