An Improved Seeker Optimization Algorithm for Phase Sensitivity Enhancement of a Franckeite- and WS2-Based SPR Biosensor for Waterborne Bacteria Detection

Micromachines (Basel). 2024 Mar 3;15(3):362. doi: 10.3390/mi15030362.

Abstract

For the purpose of detecting waterborne bacteria, a high-phase-sensitivity SPR sensor with an Ag-TiO2-Franckeite-WS2 hybrid structure is designed using an improved seeker optimization algorithm (ISOA). By optimizing each layer of sensor construction simultaneously, the ISOA guarantees a minimum reflectance of less than 0.01 by Ag (20.36 nm)-TiO2 (6.08 nm)-Franckeite (monolayer)-WS2 (bilayer) after 30 iterations for E. coli. And the optimal phase sensitivity is 2.378 × 106 deg/RIU. Sensor performance and computing efficiency have been greatly enhanced using the ISOA in comparison to the traditional layer-by-layer technique and the SOA method. This will enable sensors to detect a wider range of bacteria with more efficacy. As a result, the ISOA-based design idea could provide SPR biosensors with new applications in environmental monitoring.

Keywords: Franckeite; SPR; WS2; improved seeker optimization algorithm; phase sensitivity; waterborne bacteria.