Biomaterials in Drug Delivery: Advancements in Cancer and Diverse Therapies-Review

Int J Mol Sci. 2024 Mar 8;25(6):3126. doi: 10.3390/ijms25063126.

Abstract

Nano-sized biomaterials are innovative drug carriers with nanometric dimensions. Designed with biocompatibility in mind, they enable precise drug delivery while minimizing side effects. Controlled release of therapeutic substances enhances efficacy, opening new possibilities for treating neurological and oncological diseases. Integrated diagnostic-therapeutic nanosystems allow real-time monitoring of treatment effectiveness, which is crucial for therapy personalization. Utilizing biomaterials as nano-sized carriers in conjunction with drugs represents a promising direction that could revolutionize the field of pharmaceutical therapy. Such carriers represent groundbreaking drug delivery systems on a nanometric scale, designed with biocompatibility in mind, enabling precise drug delivery while minimizing side effects. Using biomaterials in synergy with drugs demonstrates significant potential for a revolutionary impact on pharmaceutical therapy. Conclusions drawn from the review indicate that nano-sized biomaterials constitute an innovative tool that can significantly improve therapy effectiveness and safety, especially in treating neurological and oncological diseases. These findings should guide researchers towards further studies to refine nano-sized biomaterials, assess their effectiveness under various pathological conditions, and explore diagnostic-therapeutic applications. Ultimately, these results underscore the promising nature of nano-sized biomaterials as advanced drug carriers, ushering in a new era in nanomedical therapy.

Keywords: DNA; anti-cancer therapy; biomaterials; chitosan; drug carriers; fibrin; fibroin; hyaluronic acid; nano drug delivery; nanomaterials; pectin.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials* / therapeutic use
  • Drug Carriers
  • Drug Delivery Systems / methods
  • Humans
  • Neoplasms* / drug therapy

Substances

  • Biocompatible Materials
  • Drug Carriers