An Unexpected Seminal Vesicle Pitfall in PSMA PET

Clin Nucl Med. 2024 Jun 1;49(6):e274-e275. doi: 10.1097/RLU.0000000000005183. Epub 2024 Mar 25.

Abstract

A 76-year-old man undergoing hormone therapy for prostate cancer was referred for 68 Ga-PSMA-11-PET (PSMA PET) due to persistently detectable PSA level. No PSMA-positive tumor lesions were detected, so a delayed phase imaging was performed, which revealed focal PSMA uptake in the right seminal vesicle together with contrast accumulation on excretory phase contrast-enhanced CT. These findings were finally determined to be secondary to urinary reflux as a consequence of a prostatic enucleation he had undergone 5 months earlier following an episode of acute urinary retention.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antigens, Surface*
  • Edetic Acid / analogs & derivatives
  • Gallium Isotopes*
  • Gallium Radioisotopes*
  • Glutamate Carboxypeptidase II / metabolism
  • Humans
  • Male
  • Oligopeptides
  • Positron-Emission Tomography*
  • Prostatic Neoplasms / diagnostic imaging
  • Seminal Vesicles* / diagnostic imaging

Substances

  • gallium 68 PSMA-11
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Edetic Acid
  • Oligopeptides
  • FOLH1 protein, human
  • Glutamate Carboxypeptidase II
  • Antigens, Surface