Cancer cell invasion: Caveolae and invadosomes are partners in crime

Laura Sotodosos-Alonso; Miguel A Del Pozo

doi:10.1016/j.cub.2024.02.006

Cancer cell invasion: Caveolae and invadosomes are partners in crime

Curr Biol. 2024 Mar 25;34(6):R244-R246. doi: 10.1016/j.cub.2024.02.006.

Authors

Laura Sotodosos-Alonso¹, Miguel A Del Pozo²

Affiliations

¹ Mechanoadaptation and Caveolae Biology Laboratory, Novel Mechanisms of Atherosclerosis Program, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain.
² Mechanoadaptation and Caveolae Biology Laboratory, Novel Mechanisms of Atherosclerosis Program, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain. Electronic address: madelpozo@cnic.es.

PMID: 38531317
DOI: 10.1016/j.cub.2024.02.006

Abstract

During cancer progression, tumor cells need to disseminate by remodeling the extracellular tumor matrix. A recent study sheds light on the intricate cooperation between caveolae and invadosomes that facilitates the spread of cancer cells.

MeSH terms

Caveolae
Crime
Extracellular Matrix
Humans
Neoplasm Invasiveness / pathology
Podosomes* / pathology