Living Cell as a Self-Synchronized Chemical Reactor

J Phys Chem Lett. 2024 Apr 4;15(13):3559-3570. doi: 10.1021/acs.jpclett.4c00190. Epub 2024 Mar 25.

Abstract

Thermal fluctuations power all processes inside living cells. Therefore, these processes are inherently random. However, myriad multistep chemical reactions act in concerto inside a cell, finally leading to this chemical reactor's self-replication. We speculate that an underlying mechanism in nature must exist that allows all of these reactions to synchronize at multiple time and length scales, overcoming in this way the random nature of any single process in a cell. This Perspective discusses what type of research is needed to understand this undiscovered synchronization law.

Publication types

  • Review