We describe a classic case of nasal rhinosporidiosis in a woman who resided in Johannesburg, South Africa, but originated from a rural area in Eastern Cape Province. We confirmed histologic diagnosis using PCR testing and compared details with those from records on 17 other cases from South Africa.
Keywords: PCR; Rhinosporidium; South Africa; aquatic protistan parasites; eukaryotic pathogens; fungi; histology; nasal polyps; rhinosporidiosis; scanning electron microscopy.