Hepatitis C is distributed worldwide and possesses a hidden characteristic. The traditional methods of screening and diagnosis of hepatitis C infection commonly used in clinics are based on anti-HCV antibody and HCV RNA detection. Advances in HCV antigen detection technologies can apparently reduce the window period for anti-HCV antibodies, providing new clinical evidence for the early detection, diagnosis, and treatment of HCV infection. This article is a current review of HCV antigen detection methodologies, clinical applications, and detection strategies.
丙型肝炎呈世界性分布，并具有隐匿性的特点。在临床上常用筛查和诊断丙型肝炎感染的传统方法抗-HCV抗体检测和HCV RNA检测基础上，HCV抗原检测技术的发展，可以明显缩短抗-HCV抗体的窗口期，对HCV感染的早发现、早诊断和早治疗提供新的临床依据。现从HCV抗原检测技术、临床应用、检测策略进行综述。.
Keywords: Antigen; Clinical application; Detection; Hepatitis C virus; Strategy.