Keratic Precipitates: An Overlooked Sign of Microsporidial Stromal Keratitis?

Ocul Immunol Inflamm. 2024 Mar 21:1-3. doi: 10.1080/09273948.2024.2329805. Online ahead of print.

Abstract

Purpose: To elucidate a distinctive clinical feature in cases of microsporidial stromal keratitis (MSK).

Method: A retrospective observational study of cases with a histopathological and/or microbiological diagnosis of MSK on corneal biopsy or host corneal button between 2016 and 2022 was conducted.

Results: Eighteen cases with a confirmed histopathological and/or microbiological diagnosis of MSK were detected. Careful review of slit-lamp photographs revealed the presence of pigmented keratic precipitates (KPs) beyond the area of stromal keratitis in five out of eighteen cases (27.7%).

Conclusion: The presence of pigmented KPs beyond the area of lesion can alert the clinician to keep microsporidia as a differential cause for stromal keratitis. Management can be tailored accordingly for a better outcome.

Keywords: Keratic precipitate; keratitis; microsporidia; stromal keratitis.