Principles and clinical applications of transcutaneous laser-assisted drug delivery: A narrative review

Abstract

Introduction: Transcutaneous laser-assisted drug delivery (LADD) is recognized as a developing therapy for skin disorders.

Method: Current literature was reviewed to summarize current applications for LADD.

Discussion: 12 clinical applications for this therapy are currently reported.

Conclusion: LADD has potential for wide application in skin disorder treatment.

Lay summary: Laser assisted drug delivery improves drug bioavailability for treatment of skin disorders. This technique is being assessed clinically in disorders ranging from skin cancers to alopecia.

Keywords: Transdermal drug delivery; dot array laser; drug transdermal absorption; laser-assisted drug delivery; traditional laser; transdermal absorption of macromolecules.