Cardiovascular disease risk scores in patients with optimal vs suboptimal weight loss after bariatric surgery: Translating improvements into clinical practice

Rajaa Mohamed Salih; Juan S Barajas-Gamboa; Gabriel Diaz Del Gobbo; Mohammed Abdallah; Helen Sun; Terrence Lee-St John; Oshin Kanwar; Carlos Abril; Juan Pablo Pantoja; Javed Raza; Hani Sabbour; John Rodriguez; Matthew Kroh; Ricard Corcelles

doi:10.1016/j.amjsurg.2024.03.009

Cardiovascular disease risk scores in patients with optimal vs suboptimal weight loss after bariatric surgery: Translating improvements into clinical practice

Am J Surg. 2024 Mar 11:S0002-9610(24)00169-7. doi: 10.1016/j.amjsurg.2024.03.009. Online ahead of print.

Affiliations

¹ Department of General Surgery, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
² Department of General Surgery, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
³ Department of General Surgery, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Department of General Surgery, Cleveland Clinic, Cleveland, OH, USA.
⁴ Department of Cardiology, Cleveland Clinic Abu Dhabi, United Arab Emirates; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
⁵ Department of General Surgery, Cleveland Clinic, Cleveland, OH, USA; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
⁶ Department of General Surgery, Cleveland Clinic, Cleveland, OH, USA; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA. Electronic address: corcelr@ccf.org.

PMID: 38494359
DOI: 10.1016/j.amjsurg.2024.03.009

Abstract

Introduction: The aim of this study was to evaluate cardiovascular disease (CVD) risk modification in patients with optimal weight loss (OWL) versus suboptimal weight loss SWL following MBS.

Methods: This was a retrospective analysis. The 10-year risk CVD was estimated before and after one year of surgery using the "Framingham Score".

Results: 191 patients were included in our study. Mean baseline Framingham score was 7.2 ± 6.9%. According to the score, 54% of patients were classified as low risk (n = 104), 23% as moderate (n = 43), 20% moderately high (n = 39) and 3% as high risk (n = 5). One year after surgery, 91% of the patients showed reduction of their Framingham score. Mean CVD risk score decreased significantly to 4.1 ± 3.7% when compared to baseline (p-value is < 0.001); 80% of patients classified as low risk (n = 153), 13% as moderate (n = 25), 7% moderately high (n = 13) and 0% as high risk (n = 0).

Conclusion: Weight loss after bariatric surgery reduces CVD risk scores and the magnitude of effect correlates with the degree of weight loss.

Keywords: Bariatric surgery; Cardiovascular disease; Cardiovascular risk scores; Roux-en-Y gastric bypass; Sleeve gastrectomy; Weight loss.