Endoscopic features with linked-color imaging of non- Helicobacter pylori Helicobacter-associated gastritis: a case study

Tsutomu Takeda; Daisuke Asaoka; Shu Hirai; Masahiko Nakamura; Akihito Nagahara

doi:10.1016/j.vgie.2023.10.009

Endoscopic features with linked-color imaging of non- Helicobacter pylori Helicobacter-associated gastritis: a case study

VideoGIE. 2023 Oct 21;9(3):123-127. doi: 10.1016/j.vgie.2023.10.009. eCollection 2024 Mar.

Authors

Tsutomu Takeda¹, Daisuke Asaoka², Shu Hirai³, Masahiko Nakamura⁴, Akihito Nagahara¹

Affiliations

¹ Department of Gastroenterology, Juntendo University School of Medicine, Tokyo, Japan.
² Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, Japan.
³ Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan.
⁴ Satoshi Omura Memorial Institute, Kitasato University, Tokyo, Japan.

Abstract

Background and aims: The endoscopic findings of non-Helicobacter pylori Helicobacter (NHPH) are not widely known. Linked-color imaging (LCI) has emerged as a new system for image-enhanced endoscopy (IEE) that enhances color tone and improves visibility. The aim of this case study was to assess how endoscopic findings of NHPH are enhanced with LCI.

Methods: We report the case of a 72-year-old woman in whom an NHPH species was found during EGD using LCI.

Results: The EGD did not reveal any endoscopic findings of diffuse redness, patchy redness, or atrophy. However, erosions, nonuniform redness, and crack-like mucosa were seen in the antrum, as well as LCI-enhanced endoscopic findings. In addition, nodular gastritis and a white marbled appearance were also observed in the antrum. LCI and blue-laser imaging enhanced the endoscopic findings. Floating bacterial bodies with a fine coil-like shape and diameter longer than that of H pylori were pathologically observed in the mucus, suggesting NHPH. A polymerase chain reaction test led to a diagnosis of Helicobacter suis.

Conclusions: Our case demonstrates that IEE is useful in diagnosing NHPH. The detection of NHPH using IEE enabled us to contribute to an improved diagnosis of NHPH.