The Potential of Natural Products in the Management of Cardiovascular Disease

Curr Pharm Des. 2024;30(8):624-638. doi: 10.2174/0113816128295053240207090928.

Abstract

Cardiovascular Disease (CVD) is one of the most prevalent diseases in the world, comprising a variety of disorders such as hypertension, heart attacks, Peripheral Vascular Disease (PVD), dyslipidemias, strokes, coronary heart disease, and cardiomyopathies. The World Health Organization (WHO) predicts that 22.2 million people will die from CVD in 2030. Conventional treatments for CVDs are often quite expensive and also have several side effects. This potentiates the use of medicinal plants, which are still a viable alternative therapy for a number of diseases, including CVD. Natural products' cardio-protective effects result from their anti-oxidative, anti-hypercholesterolemia, anti-ischemic, and platelet aggregation-inhibiting properties. The conventional therapies used to treat CVD have the potential to be explored in light of the recent increase in the popularity of natural goods and alternative medicine. Some natural products with potential in the management of cardiovascular diseases such as Allium sativum L., Ginkgo biloba, Cinchona ledgeriana, Ginseng, Commiphora mukul, Digitalis lanata, Digitalis purpurea L., Murrayakoenigii, Glycyrrhiza glabra, Polygonum cuspidatum, Fenugreek, Capsicum annuum, etc. are discussed in this article.

Keywords: Cardiovascular diseases; anti-hypercholesterolemia agents; anti-ischemic agents; anti-oxidative agents; natural products; platelet aggregation..

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Products* / pharmacology
  • Biological Products* / therapeutic use
  • Cardiovascular Diseases* / drug therapy
  • Humans
  • Plants, Medicinal / chemistry

Substances

  • Biological Products