Cutting-Edge Therapies for Lung Cancer

Cells. 2024 Mar 1;13(5):436. doi: 10.3390/cells13050436.

Abstract

Lung cancer remains a formidable global health challenge that necessitates inventive strategies to improve its therapeutic outcomes. The conventional treatments, including surgery, chemotherapy, and radiation, have demonstrated limitations in achieving sustained responses. Therefore, exploring novel approaches encompasses a range of interventions that show promise in enhancing the outcomes for patients with advanced or refractory cases of lung cancer. These groundbreaking interventions can potentially overcome cancer resistance and offer personalized solutions. Despite the rapid evolution of emerging lung cancer therapies, persistent challenges such as resistance, toxicity, and patient selection underscore the need for continued development. Consequently, the landscape of lung cancer therapy is transforming with the introduction of precision medicine, immunotherapy, and innovative therapeutic modalities. Additionally, a multifaceted approach involving combination therapies integrating targeted agents, immunotherapies, or traditional cytotoxic treatments addresses the heterogeneity of lung cancer while minimizing its adverse effects. This review provides a brief overview of the latest emerging therapies that are reshaping the landscape of lung cancer treatment. As these novel treatments progress through clinical trials are integrated into standard care, the potential for more effective, targeted, and personalized lung cancer therapies comes into focus, instilling renewed hope for patients facing challenging diagnoses.

Keywords: combination therapy; conventional treatment; innovative therapeutic modalities; lung cancer.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents* / therapeutic use
  • Combined Modality Therapy
  • Humans
  • Immunotherapy
  • Lung Neoplasms* / drug therapy
  • Precision Medicine

Substances

  • Antineoplastic Agents