Objectives: To explore the rules of acupoint selection and compatibility of acupuncture for Tourette syndrome(TS) in children.
Methods: The relevant literature regarding acupuncture for Tourette syndrome in children included in CNKI, Wanfang, VIP, SinoMed, PubMed, Web of Science and Cochrane Library from the establishment of the database to March 31st, 2023 was retrieved.The information of acupuncture prescription, syndrome type, meridian affinity was extracted to set up database. The Microsoft Excel 2019 was used for descriptive statistical analysis, SPSS modeler18.0 was for association rule analysis, lantern5.0 was for latent structure analysis and comprehensive clustering.
Results: ①A total of 80 literature was included, and 112 acupuncture prescriptions were extracted, involving 104 acupoints, with a cumulative frequency of 859 times.②The acupoints with high use frequency were Taichong(LR 3), Baihui(GV 20), Fengchi(GB 20), Hegu(LI 4), Sishencong(EX-HN 1), Sanyinjiao(SP 6) and Zusanli(ST 36).③In the treatment of TS with acupuncture, the governor vessel acupoints were the most frequently used, the proportion of acupoints on the head, face, neck and lower limbs was higher. ④The association rule analysis showed that Fengchi(GB 20)-Hegu(LI 4) and Taichong(LR 3)-Hegu(LI 4) had the highest support degree, both were 47.32%.⑤Five comprehensive clustering models were obtained by analyzing the latent structure of high-frequency acupoints, corresponding to yin deficiency disturbing wind, liver hyperactivity and spleen deficiency, liver yang transforming into wind, phlegm-heat harassing the interior and qi stagnation transformed fire.
Conclusions: Acupuncture for TS in children is based on the principle of soothe the liver and extinguish the wind, regulating qi and blood, and paying attention to regulating spirit and qi. The core acupoints are Fengchi(GB 20), Hegu(LI 4), Taichong(LR 3), Baihui(GV 20), Sanyinjiao(SP 6) , Zusanli(ST 36), acupoints should be selected according to different syndrome in clinical.
目的: 探究针刺治疗儿童Tourette综合征（TS）的选穴及配伍规律。方法: 检索中国期刊全文数据库（CNKI）、万方数据知识服务平台（Wanfang）、维普资讯中文期刊服务平台（VIP）、中国生物医学文献数据库（SinoMed）、PubMed、Web of Science、Cochrane Library建库至2023年3月31日针刺治疗儿童Tourette综合征的相关文献，提取针刺处方、证候类型、归经等信息建立数据库，采用Microsoft Excel 2019进行描述性统计分析，采用SPSS modeler18.0进行关联规则分析，采用lantern5.0进行隐结构分析并综合聚类。结果: ①共纳入文献80篇，提取针刺处方112个，涉及腧穴104个，累计使用频次859次；②使用频次较高的腧穴有太冲、百会、风池、合谷、四神聪、三阴交、足三里；③针刺治疗TS以督脉腧穴应用最多，头面颈部、下肢部腧穴占比较高；④关联规则以风池-合谷、太冲-合谷支持度最高，均为47.32%；⑤对高频腧穴隐结构分析得到5种综合聚类模型，分别对应阴虚动风证、肝旺脾虚证、肝阳化风证、痰热内扰证、气郁化火证。结论: 针刺治疗儿童TS以平肝熄风、调摄气血为原则，注重调神与调气，核心穴组为风池、合谷、太冲、百会、三阴交、足三里，临证当根据不同证候类型辨证选穴。.
Keywords: Tourette syndrome; acupuncture; children; data mining; gilles de la Tourette syndrome; rules of acupoint selection.