Pediatric splenic infarction: Assessment of associated clinical conditions and outcome

Pediatr Blood Cancer. 2024 Jun;71(6):e30939. doi: 10.1002/pbc.30939. Epub 2024 Mar 10.

Abstract

Pediatric splenic infarction (SI) is rare yet clinically significant. Publications regarding this complication are mostly limited to case reports. This is a retrospective study examining SI etiology, clinical presentation, management, and outcomes among children. Twenty-two patients (median age: 7.9 years) were included, mostly with pre-existing hematological diseases. Splenomegaly (72%), thrombocytopenia, and anemia were common. Most of the patients did not receive antithrombotic therapy yet only two patients experienced recurrences. During follow up 36% of patients died, however no fatalities were attributed to thrombotic or bleeding complications.

Keywords: children; pediatric; spleen; splenic infarction; treatment.