Liposomal bupivacaine for ultrasound-guided rectus sheath blocks after midline laparotomy

Anaesth Rep. 2024 Mar 7;12(1):e12284. doi: 10.1002/anr3.12284. eCollection 2024 Jan-Jun.

Abstract

Optimal pain management after open abdominal surgery is essential but can be difficult to achieve. The effects of inadequate analgesia go beyond the first few postoperative days; severe acute postoperative pain may contribute to the development of chronic postsurgical pain. Thoracic epidural analgesia is a traditional approach to the management of acute pain after open abdominal surgery but has multiple possible contraindications and can be technically challenging. In our hospital, we typically offer ultrasound-guided rectus sheath blocks with catheters when epidural analgesia is not feasible. However, the recent registration of long-acting liposomal bupivacaine in the Netherlands as well as logistical and equipment-related issues have led us to consider liposomal bupivacaine as an alternative to the use of catheters. Here, we present a short case series to describe our first clinical experiences with the use of liposomal bupivacaine in ultrasound-guided rectus sheath blocks after midline laparotomy for three patients in whom epidural insertion was contraindicated.

Keywords: anaesthetics; bupivacaine; laparotomy; local; pain; postoperative.

Publication types

  • Case Reports