Trichodysplasia Spinulosa

Sultan Qaboos Univ Med J. 2024 Feb;24(1):131-134. doi: 10.18295/squmj.5.2023.035. Epub 2024 Feb 28.

Abstract

Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in a setting of immunosuppression. It is caused by a novel human polymoavirus, TS-associated polyomavirus. Reduction of immunosuppression and/or anti-viral therapy is the main therapeutic strategies used to treat such cases. We report a biopsy-proven case of TS in a male renal transplant patient who presented to a dermatology outpatient clinic in Montreal, Canada, in 2015. He was managed with valgancyclovir with no obvious response. Subsequently, a trial of topical imiquimod was commenced. Awareness of TS can prompt early diagnosis and management to prevent possible complications.

Keywords: Canada; Case Report; Human Polyomavirus; Immunosuppression; Organ Transplant.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Canada
  • Humans
  • Male
  • Skin Diseases*