Functional Mitral Regurgitation: Patient Selection and Optimization

Pooja Prasad; Pranav Chandrashekar; Harsh Golwala; Conrad J Macon; Johannes Steiner

doi:10.1016/j.iccl.2023.11.001

Functional Mitral Regurgitation: Patient Selection and Optimization

Interv Cardiol Clin. 2024 Apr;13(2):167-182. doi: 10.1016/j.iccl.2023.11.001. Epub 2024 Jan 20.

Authors

Pooja Prasad¹, Pranav Chandrashekar², Harsh Golwala², Conrad J Macon², Johannes Steiner³

Affiliations

¹ Division of Cardiology, University of California-San Francisco, 505 Parnassus Avenue, Suite M1182, Box 0124, San Francisco, CA 94143, USA.
² Knight Cardiovascular Institute, Oregon Health & Science University, 3161 SW Pavilion Loop, Portland, OR 97239, USA.
³ Knight Cardiovascular Institute, Oregon Health & Science University, 3161 SW Pavilion Loop, Portland, OR 97239, USA. Electronic address: steinejo@ohsu.edu.

PMID: 38432760
DOI: 10.1016/j.iccl.2023.11.001

Abstract

Functional mitral regurgitation appears commonly among all heart failure phenotypes and can affect symptom burden and degree of maladaptive remodeling. Transcatheter mitral valve edge-to-edge repair therapies recently became an important part of the routine heart failure armamentarium for carefully selected and medically optimized candidates. Patient selection is considering heart failure staging, relevant comorbidities, as well as anatomic criteria. Indications and device platforms are currently expanding.

Keywords: Functional mitral regurgitation; Heart failure; Secondary mitral regurgitation; Transcatheter edge-to-edge repair.

Publication types

Review

MeSH terms

Heart Failure* / surgery
Humans
Mitral Valve Insufficiency* / diagnosis
Mitral Valve Insufficiency* / surgery
Patient Selection
Symptom Burden