Bariatric Surgery and New-Onset Substance Use Disorders: A Systematic review and Meta-analysis

Obes Surg. 2024 Apr;34(4):1366-1375. doi: 10.1007/s11695-024-07130-7. Epub 2024 Mar 2.

Abstract

Increasing evidence suggests that bariatric surgery (BS) patients are at risk for substance abuse disorders (SUD). The purpose of this systematic review and meta-analysis was to determine the relationship between BS and the development of new-onset substance abuse disorder (SUDNO) in bariatric patients. On October 31, 2023, we reviewed the scientific literature following PRISMA guidelines. A total of 3242 studies were analyzed, 7 met the inclusion criteria. The pooled incidence of SUDNO was 4.28%. Patients' characteristics associated with SUDNO included preoperative mental disorders, high pre-BS BMI, and public health insurance. Surgical factors associated with new SUDNOs included severe complications in the peri- or postoperative period. The occurrence of SUDNOs is a non-negligeable complication after BS. Predisposing factors may be identified and preventive actions undertaken.

Keywords: Bariatric Surgery; New-onset Substance Use Disorder; Obesity; Substance Use.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Review

MeSH terms

  • Bariatric Surgery*
  • Humans
  • Obesity, Morbid* / surgery
  • Postoperative Period
  • Preoperative Period
  • Substance-Related Disorders* / complications
  • Substance-Related Disorders* / epidemiology