Inhalation Injury, Respiratory Failure, and Ventilator Support in Acute Burn Care

Sai R Velamuri; Yasmin Ali; Julio Lanfranco; Pooja Gupta; David M Hill

doi:10.1016/j.cps.2023.11.001

Inhalation Injury, Respiratory Failure, and Ventilator Support in Acute Burn Care

Clin Plast Surg. 2024 Apr;51(2):221-232. doi: 10.1016/j.cps.2023.11.001. Epub 2023 Nov 23.

Authors

Sai R Velamuri¹, Yasmin Ali², Julio Lanfranco³, Pooja Gupta⁴, David M Hill⁵

Affiliations

¹ Department of Surgery, College of Medicine, University of Tennessee, Health Science Center, Memphis, TN 38103, USA. Electronic address: svelamur@uthsc.edu.
² Department of Surgery, College of Medicine, University of Tennessee Health Science Center, 910 Madison Avenue, 2nd floor Suite 217, Memphis, TN 38103, USA.
³ Division of Pulmonary and Critical Care, University of Tennessee Health Science Center, 965 Court Avenue Room H316B, Memphis, TN 38103, USA.
⁴ Pulmonary and Critical Care, University of Tennessee Health Science Center, 965 court avenue, Room H316B, Memphis, TN 38103, USA.
⁵ Department of Pharmacy, Regional One Health, University of Tennessee, 80 madison avenue, Memphis TN 38103, USA.

PMID: 38429045
DOI: 10.1016/j.cps.2023.11.001

Abstract

Sustaining an inhalation injury increases the risk of severe complications and mortality. Current evidential support to guide treatment of the injury or subsequent complications is lacking, as studies either exclude inhalation injury or design limit inferences that can be made. Conventional ventilator modes are most commonly used, but there is no consensus on optimal strategies. Settings should be customized to patient tolerance and response. Data for pharmacotherapy adjunctive treatments are limited.

Keywords: Acute lung injury; Burns; Extracorporeal circulation; Inhalation injury; Mechanical; Therapeutics; Ventilators.

Publication types

Review

MeSH terms

Burns*
Consensus
Critical Care
Humans
Respiratory Insufficiency* / etiology
Respiratory Insufficiency* / therapy
Ventilators, Mechanical