Toward Application of Polygenic Risk Scores to Both Enhance and Deintensify Breast Cancer Screening

J Clin Oncol. 2024 May 1;42(13):1462-1465. doi: 10.1200/JCO.24.00029. Epub 2024 Feb 29.

Authors

Kara N Maxwell^{1

2

3}, Susan M Domchek^{1

2}

Affiliations

¹ Division of Hematology/Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
² Basser Center for BRCA, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA.
³ Corporal Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA.

PMID: 38422469
PMCID: PMC11095852 (available on 2025-05-01)
DOI: 10.1200/JCO.24.00029

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Editorial

MeSH terms

Breast Neoplasms* / diagnosis
Breast Neoplasms* / genetics
Early Detection of Cancer* / methods
Female
Genetic Predisposition to Disease
Genetic Risk Score
Humans
Multifactorial Inheritance*
Risk Assessment
Risk Factors

Grants and funding