Recurrent Synovial Sarcoma with Breast and Pulmonary Nodule: A Case Report

JNMA J Nepal Med Assoc. 2024 Jan 2;62(269):52-54. doi: 10.31729/jnma.8408.

Abstract

Synovial sarcoma is a mesenchymal tumour with partial epithelial differentiation. About 85-90% of SS occur in the extremities. We present a case of a 44-year-old woman diagnosed with recurrent synovial sarcoma with breast and pulmonary nodules. The primary treatment for synovial sarcoma is wide surgical excision, while chemotherapy is reserved for metastatic cases. In the first-line metastatic setting, combination treatment with adriamycin and ifosfamide is administered. Despite the unfavourable prognosis, the patient's extended survival is fortunately not the typical outcome.

Keywords: case reports; chemotherapy; immunohistochemistry; synovial sarcoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Combined Modality Therapy
  • Doxorubicin / therapeutic use
  • Female
  • Humans
  • Ifosfamide / therapeutic use
  • Prognosis
  • Sarcoma, Synovial* / diagnosis
  • Sarcoma, Synovial* / surgery

Substances

  • Ifosfamide
  • Doxorubicin