Newly Identified Mycobacterium africanum Lineage 10, Central Africa

Emerg Infect Dis. 2024 Oct;30(3):560-563. doi: 10.3201/eid3003.231466.

Abstract

Analysis of genome sequencing data from >100,000 genomes of Mycobacterium tuberculosis complex using TB-Annotator software revealed a previously unknown lineage, proposed name L10, in central Africa. Phylogenetic reconstruction suggests L10 could represent a missing link in the evolutionary and geographic migration histories of M. africanum.

Keywords: Democratic Republic of the Congo; L10; Mycobacterium tuberculosis; TB; bacteria; central Africa; lineage 10; pathogen diversification; respiratory infections; tuberculosis and other mycobacteria; tuberculosis emergence.

MeSH terms

  • Africa, Central / epidemiology
  • Biological Evolution*
  • Mycobacterium* / genetics
  • Phylogeny
  • Software