Ovarian malignancy in an individual with 46,XY ovotesticular disorder of sexual development - A case report

James I Griggers; Robert Higgins; Martha K Terris

doi:10.1016/j.eucr.2024.102680

Ovarian malignancy in an individual with 46,XY ovotesticular disorder of sexual development - A case report

Urol Case Rep. 2024 Feb 14:53:102680. doi: 10.1016/j.eucr.2024.102680. eCollection 2024 Mar.

Authors

James I Griggers¹, Robert Higgins², Martha K Terris³

Affiliations

¹ Medical College of Georgia, Augusta University, GA, USA.
² Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
³ Department of Urology, Medical College of Georgia, Augusta University, Augusta, GA, USA.

Abstract

Disorders of sexual development (DSD) are diseases resulting from aberrations in sex chromosomes, gonadal, and internal/external genitalia development resulting in various phenotypes. Ovotesticular DSD represents a rarer entity in this classification of disorders characterized by simultaneous presence of testicular and ovarian tissue. Gonadal tumors in those with DSDs is a known risk, although ovarian masses discovered in adults with ovotesticular DSD is a rare entity and there is little literature pertaining to this population. We present a case of an incidental adnexal mass discovered in an elderly patient ultimately elucidated as a malignant ovarian mass.

Keywords: Disorder of sexual development; Intersex; Ovarian mass; Ovotesticular; True hermaphrodite.

Publication types

Case Reports