Resection of Renal Cell and Prostate Carcinoma Sternum Metastases with Long-Term Follow-Up: A Report of 2 Cases

Pascal A Berdat; Paul R Vogt; Pascal A Schai; Michael O Kurrer; Christian Rüedi; Michael B Brück; G Ulrich Exner

doi:10.1159/000536350

Resection of Renal Cell and Prostate Carcinoma Sternum Metastases with Long-Term Follow-Up: A Report of 2 Cases

Case Rep Oncol. 2024 Feb 23;17(1):352-360. doi: 10.1159/000536350. eCollection 2024 Jan-Dec.

Authors

Pascal A Berdat¹, Paul R Vogt¹, Pascal A Schai², Michael O Kurrer³, Christian Rüedi⁴, Michael B Brück⁵, G Ulrich Exner⁶

Affiliations

¹ Heart Care Medical AG, Zurich, Switzerland.
² Luzerner Kantonsspital Wolhusen, Wolhusen, Switzerland.
³ Pathologicum, Gemeinschaftspraxis für Pathologie, Zurich, Switzerland.
⁴ Operative Urology Hirslanden, Zurich, Switzerland.
⁵ Implantcast Suisse SA, Basel, Switzerland.
⁶ Orthopaedie Zentrum Zurich Klinik Hirslanden, Zurich, Switzerland.

Abstract

Introduction: Rarely solitary sternum metastases are addressed by resection. Two additional cases are presented as they are interesting because of their long-term follow-up.

Case presentation: Case 1: A renal cell carcinoma was treated by transabdominal nephrectomy at age 64. Right iliac bone and sternum metastases were diagnosed 7 months later and treated by internal hemipelvectomy followed by sternum metastasectomy 6 weeks after the internal hemipelvectomy. At 12-year follow-up, the patient appears disease free. Case 2: Prostate cancer was treated by prostatectomy at age 67. A subsequent solitary sternum metastasis was resected 10 years later for persistent PSA-activity despite repeated radiotherapy. The patient remains asymptomatic for 3 years now.

Conclusion: Resection of sternum metastases may have curative potential and should be considered in tumours known to be rather resistant to chemo- and/or radiotherapy.

Keywords: Prostate carcinoma; Renal cell carcinoma; Sternum metastasis.

Publication types

Case Reports

Grants and funding

The authors received no financial support for the research, authorship, and publication of this article. The research did not receive any specific grant.