Amphiregulin in lung diseases: A review

Medicine (Baltimore). 2024 Feb 23;103(8):e37292. doi: 10.1097/MD.0000000000037292.

Abstract

Amphiregulin is a member of the EGFR family, which is involved in many physiological and pathological processes through its binding with EGFR. Studies have found that amphiregulin plays an important role in the occurrence and development of lung diseases. This paper mainly reviews the structure and function of amphiregulin and focuses on the important role of amphiregulin in lung diseases.

Publication types

  • Review

MeSH terms

  • Amphiregulin / metabolism
  • ErbB Receptors / metabolism
  • Humans
  • Lung Diseases*
  • Signal Transduction* / physiology

Substances

  • Amphiregulin
  • ErbB Receptors