Novel and experimental therapeutics for the management of motor and non-motor Parkinsonian symptoms

Neurol Sci. 2024 Feb 23. doi: 10.1007/s10072-023-07278-7. Online ahead of print.

Abstract

BACKGROUND : Both motor and non-motor symptoms of Parkinson's disease (PD) have a substantial detrimental influence on the patient's quality of life. The most effective treatment remains oral levodopa. All currently known treatments just address the symptoms; they do not completely reverse the condition.

Methodology: In order to find literature on the creation of novel treatment agents and their efficacy for PD patients, we searched PubMed, Google Scholar, and other online libraries.

Results: According to the most recent study on Parkinson's disease (PD), a great deal of work has been done in both the clinical and laboratory domains, and some current scientists have even been successful in developing novel therapies for PD patients.

Conclusion: The quality of life for PD patients has increased as a result of recent research, and numerous innovative medications are being developed for PD therapy. In the near future, we will see positive outcomes regarding PD treatment.

Keywords: Clinical trials of novel molecules; New drug development; PD pathology; Parkinson’s disease.

Publication types

  • Review