Stereoselectivity of paclobutrazol enantiomers to oxidative stress in wheat

Chirality. 2024 Feb;36(2):e23638. doi: 10.1002/chir.23638.

Abstract

Chiral pesticides have the special chiral structures, so enantioselective biological effects are usually observed in living organisms. Current study used paclobutrazol as a case study and explored the enantioselective degradation and oxidative stress effect on wheat. The results demonstrated that the degradation of R-paclobutrazol was faster than S-paclobutrazol significantly and improved the content of MDA and O2 - in wheat plants, which proved that the R-paclobutrazol induced oxidative damage in wheat, showing selective biological effects, and S-paclobutrazol was friendly to wheat. This study provided a theoretical basis for the selective activity of chiral pesticides and the development of chiral pesticide monomers.

Keywords: bioactivity; chirality; enantiomer; oxidative damage; selectivity.

MeSH terms

  • Oxidative Stress
  • Pesticides* / chemistry
  • Stereoisomerism
  • Triazoles*
  • Triticum* / metabolism

Substances

  • paclobutrazol
  • Pesticides
  • Triazoles