Opening the KV3.1 gates: A therapeutic strategy for progressive myoclonus epilepsy type 7?

Cell Rep Med. 2024 Feb 20;5(2):101425. doi: 10.1016/j.xcrm.2024.101425.

Abstract

Progressive myoclonus epilepsy type 7, a debilitating neurological disorder, is caused by a loss-of-function mutation in the KV3.1 channel. Exciting work by Feng et al.1 utilizes a new knockin mouse model to identify a potential therapeutic intervention.

MeSH terms

  • Animals
  • Mice
  • Mutation
  • Myoclonic Epilepsies, Progressive* / genetics