Incidence of Prostate Cancer in Transgender Women Undergoing Androgen Deprivation Therapy: A Review

Indian J Endocrinol Metab. 2023 Nov-Dec;27(6):476-479. doi: 10.4103/ijem.ijem_53_23. Epub 2024 Jan 11.

Abstract

Transwomen frequently undergo androgen deprivation therapy (ADT) incorporated with oestrogen, but they are still prone to the occurrence of prostatic cancer since the prostate remains intact. The probability of this clinical condition reduces as compared with the general male population. This study aimed to study the occurrence of prostatic malignancy under hormonal therapy such as ADT in transwomen. An extensive literature search was performed using online searches on transgender health, centring on the incidence, diagnosis, treatment and management of prostate cancer in transgender women. Original articles from 1975 to 2022 were searched using PubMed, Scopus, EMBASE, DOAJ and Cochrane databases. Physical, mental and communal deliberation of health development is the major constituent of trans-health. It exhibits a fivefold reduction in prostatic malignancies in transwomen undergoing hormonal therapy contrasted with the extensive male community of indistinguishable age.

Keywords: Androgen deprivation therapy; prostate cancer; transgender.

Publication types

  • Review