Mechanical Tricuspid Valve Thrombosis Successfully Treated With Tissue Plasminogen Activator

Rebecca Haraf; Tamara Atkinson; Dai-Trang Elizabeth Le; Bhaskar Arora

doi:10.1016/j.jaccas.2023.102180

Mechanical Tricuspid Valve Thrombosis Successfully Treated With Tissue Plasminogen Activator

JACC Case Rep. 2023 Dec 29;29(3):102180. doi: 10.1016/j.jaccas.2023.102180. eCollection 2024 Feb 7.

Authors

Rebecca Haraf^{1

2}, Tamara Atkinson¹, Dai-Trang Elizabeth Le¹, Bhaskar Arora¹

Affiliations

¹ Department of Cardiology, VA Portland Health Care System, Portland, Oregon, USA.
² Knight Cardiovascular Institute, Oregon Health and Science University, Portland, Oregon, USA.

Abstract

Prosthetic mechanical valve thrombosis has traditionally been managed with urgent surgical intervention. However, the risk of redo sternotomy can be prohibitively high in some patients. Thrombolytic therapy as a noninvasive treatment of mechanical valve thrombosis is a well-recognized alternative, but optimal dosing and patient selection remain incompletely characterized for right-side mechanical valves.

Keywords: 3D echocardiography; fluoroscopy; mechanical tricuspid valve; thrombolytics; thrombosis; tissue plasminogen activator.

Publication types

Case Reports