Takayasu's Arteritis: An Uncommon Cause of Hemorrhagic Stroke in Young Individuals

Cureus. 2024 Jan 15;16(1):e52301. doi: 10.7759/cureus.52301. eCollection 2024 Jan.

Abstract

The aorta is particularly damaged by Takayasu's arteritis (TA), a rare form of vasculitis. Chest discomfort, exhaustion, fever, elevated blood pressure, heart failure, and stroke can all result from this. Major intimal fibrosis with vascular constriction is the disease's hallmark; although anybody can have it, Asian females in their 20s or 30s seem to be most typically affected. The treatment of a 23-year-old Asian female with Takayasu's arteritis (TA) is discussed in this case study, along with her presentation. Before developing seizures, the patient first showed signs of left-sided weakness and facial droop. Ischemic infarcts and vasculopathy were detected by imaging. The patient fulfilled several American College of Rheumatology (ACR) criteria for TA with a positive erythrocyte sedimentation rate (ESR). During treatment, high-dose prednisolone, cyclophosphamide, and neuroprotective measures were used. The patient's attentiveness and mobility improved despite early complications, such as vascular friability. This case illustrates the difficulties and effective treatment of neurovascular problems connected to TA.

Keywords: aorta; asian woman; cyclophosphamide; ischemic infarcts; neurovascular complications; prednisolone; seizures; takayasu's arteritis; vasculitis.

Publication types

  • Case Reports