Device's design and clinical perspectives for resistant hypertension therapy

Int J Cardiol Cardiovasc Risk Prev. 2024 Jan 23:20:200240. doi: 10.1016/j.ijcrp.2024.200240. eCollection 2024 Mar.

Abstract

Introduction: Hypertension is the leading cause of death in the cardiovascular system. Indeed, untreated hypertension can affect one's general health, but medicine can help hypertensive people reduce their chance of developing high blood pressure. However, secondary hypertension remains an unresolved illness.

Areas covered: This review will go through the typical and unusual device-based therapies for resistant hypertension that have arisen in recent years. Further to that, the innovations developed in device-based RH treatment will be covered, as well as the research and studies assessing these novel technologies.

Expert opinion: The innovative device-based techniques that target resistant hypertension provide a potential therapy that has been backed by a number of studies and clinical trials, whereas pharmacological non-adherence and increased sympathetic activity are recognized to be the primary causes of resistant hypertension. Nevertheless, some limitations will be critical for the future of these RH systems, with the device's design and larger RCTs playing a significant role in determining whether a position in routine treatment could be warranted.

Keywords: Clinical trials; Device's design; Device-based therapy; Secondary hypertension; Sympathetic nerve activity.

Publication types

  • Review