Envision the future of precision medicine in pediatric cancer

Cancer Cell. 2024 Feb 12;42(2):177-179. doi: 10.1016/j.ccell.2024.01.006.

Abstract

Exploring the diversity within the tumor microenvironment (TME) can offer crucial insights to steer cancer therapy toward precision medicine. In this issue of Cancer Cell, Wienke et al. undertake a comprehensive single-cell analysis of neuroblastoma, unveiling its immune landscape and identifying NECTIN2-TIGIT as a promising target for immunotherapy.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Child
  • Humans
  • Immunotherapy
  • Neuroblastoma* / genetics
  • Neuroblastoma* / therapy
  • Precision Medicine*
  • Single-Cell Analysis
  • Tumor Microenvironment