Neonicotinoid insecticides in plant-derived Foodstuffs: A review of separation and determination methods based on liquid chromatography

Bingxin Yang; Mengling Tu; Sheng Wang; Wen Ma; Yunxiao Zhu; Zhiyong Ma; Xianjiang Li

doi:10.1016/j.foodchem.2024.138695

Neonicotinoid insecticides in plant-derived Foodstuffs: A review of separation and determination methods based on liquid chromatography

Food Chem. 2024 Jun 30:444:138695. doi: 10.1016/j.foodchem.2024.138695. Epub 2024 Feb 9.

Authors

Bingxin Yang¹, Mengling Tu², Sheng Wang², Wen Ma³, Yunxiao Zhu⁴, Zhiyong Ma⁵, Xianjiang Li⁶

Affiliations

¹ Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, State Key Laboratory of Organic-Inorganic Composites, College of Chemical Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
² Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China.
³ State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
⁴ Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China; State Key Laboratory of Heavy Oil Processing, College of Chemical Engineering and Environment, China University of Petroleum, Beijing 102249, China.
⁵ Beijing Advanced Innovation Center for Soft Matter Science and Engineering, State Key Laboratory of Organic-Inorganic Composites, College of Chemical Engineering, Beijing University of Chemical Technology, Beijing 100029, China. Electronic address: mazhy@mail.buct.edu.cn.
⁶ Key Laboratory of Chemical Metrology and Applications on Nutrition and Health for State Market Regulation, Division of Metrology in Chemistry, National Institute of Metrology, Beijing 100029, China. Electronic address: lixianjiang@nim.ac.cn.

PMID: 38346362
DOI: 10.1016/j.foodchem.2024.138695

Abstract

Neonicotinoids (NEOs) are the most widely used insecticides globally. They can contaminate or migrate into foodstuffs and exert severe neonic toxicity on humans. Therefore, lots of feasible analytical methods were developed to assure food safety. Nevertheless, there is a lack of evaluation that the impacts of food attributes on the accurate determination of NEOs. This review aims to provide a comprehensive overview of sample preparation methods regarding 6 categories of plant-derived foodstuffs. Currently, QuEChERS as the common strategy can effectively extract NEOs from plant-derived foodstuffs. Various enrichment technologies were developed for trace levels of NEOs in processed foodstuffs, and multifarious novel sorbents provided more possibility for removing complex matrices to lower matrix effects. Additionally, detection methods based on liquid chromatography were summarized and discussed in this review. Finally, some limitations were summarized and new directions were proposed for better advancement.

Keywords: Liquid chromatography; Neonicotinoids; Plant-derived foodstuffs; Sample preparation.

Publication types

Review

MeSH terms

Chromatography, Liquid
Food
Food Safety
Humans
Insecticides* / analysis
Neonicotinoids / analysis

Substances

Insecticides
Neonicotinoids