Morphofunctional State of the Ovaries in Rats with Experimental Model of Functional Cysts and Their Treatment with Gonadotropin-Releasing Hormone Antagonist

Bull Exp Biol Med. 2024 Jan;176(3):407-410. doi: 10.1007/s10517-024-06034-x. Epub 2024 Feb 12.

Abstract

The morphofunctional features of the ovaries were evaluated in rats with functional ovarian cysts model treated with gonadotropin-releasing hormone antagonist. Administration of the antagonist significantly (p=0.009) reduced the number of cysts and the growth of follicles in the ovaries. The obtained results attest to a possibility of successful treatment of functional ovarian cysts with gonadotropin-releasing hormone antagonist.

Keywords: functional ovarian cysts; functional ovarian cysts treatment; gonadotropin-releasing hormone antagonist; ovarian morphology.

MeSH terms

  • Animals
  • Cysts*
  • Female
  • Gonadotropin-Releasing Hormone
  • Humans
  • Models, Theoretical
  • Ovarian Cysts* / drug therapy
  • Rats

Substances

  • Gonadotropin-Releasing Hormone