Imaging in hepatopulmonary syndrome-case report. A multicenter approach during the coronavirus pandemic

J Radiol Case Rep. 2023 Oct 31;17(10):1-13. doi: 10.3941/jrcr.v17i8.4411. eCollection 2023 Oct.

Abstract

A 60-year-old lady with alcoholic liver disease developed central cyanosis and orthodeoxia. A technetium-99m macro-aggregated albumin lung perfusion scan and contrast echocardiogram were performed. A 13% right to left shunt was calculated from the macro-aggregated albumin scan. There were more bubbles in the left heart than the right at the end of the contrast echocardiogram. Hepatopulmonary syndrome was therefore diagnosed. The patient had a liver transplant five days after these investigations. Further discussion about hepatopulmonary syndrome will be provided. Normally, macro-aggregated albumin scans are performed in few centers, however as this was at the height of the coronavirus pandemic, the scan needed to be performed locally to reduce the chance of the patient getting coronavirus. Local radiographers were remotely instructed on conducting the macro-aggregated albumin scan by a larger center to provide a timely and important investigation in a logistically difficult scenario.

Keywords: COVID-19 Pandemic; Contrast Echocardiography; Hepatopulmonary Syndrome; Interdepartmental Relations; Liver; Lungs; Nuclear Medicine; Right-to-Left Shunt; Technetium Tc 99m Aggregated Albumin.

Publication types

  • Multicenter Study
  • Case Reports

MeSH terms

  • Albumins
  • Coronavirus*
  • Female
  • Hepatopulmonary Syndrome* / diagnostic imaging
  • Hepatopulmonary Syndrome* / etiology
  • Humans
  • Lung
  • Middle Aged
  • Pandemics
  • Radiopharmaceuticals
  • Technetium Tc 99m Aggregated Albumin

Substances

  • Technetium Tc 99m Aggregated Albumin
  • Albumins
  • Radiopharmaceuticals