Relations between glomerular hyperfiltration and podocyte injury: potential role of Piezo1 in the Rac1-mineralocorticoid receptor activation pathway

Hypertens Res. 2024 Apr;47(4):1092-1094. doi: 10.1038/s41440-024-01603-z. Epub 2024 Feb 9.

Authors

Yuichi Yoshida¹, Hirotaka Shibata²

Affiliations

¹ Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University, Yufu, Japan.
² Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University, Yufu, Japan. hiro-405@cb3.so-net.ne.jp.

PMID: 38337007
DOI: 10.1038/s41440-024-01603-z

No abstract available

Keywords: Hypertension; Mineralocorticoid receptor; Piezo1; Podocyte; Rac1.

Publication types

Editorial
Comment

MeSH terms

Humans
Hypertension, Renal* / metabolism
Ion Channels / metabolism
Mineralocorticoids / metabolism
Nephritis*
Podocytes* / metabolism
Receptors, Mineralocorticoid / metabolism

Substances

Receptors, Mineralocorticoid
Mineralocorticoids
Ion Channels

Supplementary concepts

Hypertensive Nephropathy