The global state of research in stem cells therapy for spinal cord injury (2003-2022): a visualized analysis

Taoyu Chen; Jiaying Zhu; Gang Wang; Jinlei Sun; Xiaofeng Ma; Lijun Tian; Meiling Zhang; Fengyan Wang; Ze Yu

doi:10.3389/fnins.2024.1323383

The global state of research in stem cells therapy for spinal cord injury (2003-2022): a visualized analysis

Front Neurosci. 2024 Jan 24:18:1323383. doi: 10.3389/fnins.2024.1323383. eCollection 2024.

Authors

Taoyu Chen^#¹, Jiaying Zhu^#², Gang Wang¹, Jinlei Sun¹, Xiaofeng Ma¹, Lijun Tian¹, Meiling Zhang³, Fengyan Wang³, Ze Yu¹

Affiliations

¹ Department of Orthopedics, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, China.
² College of Pharmacy, China Pharmaceutical University, Nanjing, China.
³ Department of Orthopedics, 981st Hospital of the Chinese People's Liberation Army Joint Logistics Support Force, Chengde, China.

^# Contributed equally.

Abstract

Objective: Our study aimed to visualize the global status and frontiers in stem cell therapy for spinal cord injury by using bibliometric methodology.

Methods: Publication citation information related to stem cell therapy for spinal cord injury (SCI) studies between 2003 and 2022 was retrieved from the Web of Science Core Collection database. For the visualized study, VOS viewer software and Graph Pad Prism 9.5 were used to perform bibliometric analysis of included data and publication number statistics in stem cell therapy for the SCI domain.

Results: A total of 6,686 publications were retrieved. The USA and China made the highest contributions to global research with the highest number of citations and link strength. The journal Experimental Neurology ranks as the top journal, combining the publication amount and bibliometrics results. The University of Toronto, based in Canada, was the first-ranking institution. The directions of the current study could be divided into five clusters. The research of Transplantation and Regenerative Medicine and Neurosciences Mechanism Research may be the emerging frontiers in this domain.

Conclusion: In summary, stem cell therapy for spinal cord injuries is poised for more valuable advances.

Keywords: bibliometrics; research Frontiers; spinal cord injury; stem cell; visualized study.

Publication types

Review

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Education Department of Natural Science General Project of Inner Mongolia Autonomous Region in 2022 (Grant number: NJZY22091). General Program of Natural Science Foundation of Hebei Province of China, (Grant number H2020406027); the Medical Science and Technology Youth Cultivation Project of the Chinese People’s Liberation Army, (Grant number 16QNP074).