Inhalation of particulate matter containing environmentally persistent free radicals induces endothelial dysfunction mediated via AhR activation at the air-blood interface

Ankit Aryal; Ashlyn C Harmon; K J Varner; Alexandra Noël; Stephania A Cormier; Divine B Nde; Peter Mottram; Jemiah Maxie; Tammy R Dugas

doi:10.1093/toxsci/kfae007

Inhalation of particulate matter containing environmentally persistent free radicals induces endothelial dysfunction mediated via AhR activation at the air-blood interface

Toxicol Sci. 2024 Feb 3:kfae007. doi: 10.1093/toxsci/kfae007. Online ahead of print.

Authors

Ankit Aryal¹, Ashlyn C Harmon¹, K J Varner², Alexandra Noël¹, Stephania A Cormier³, Divine B Nde⁴, Peter Mottram⁵, Jemiah Maxie¹, Tammy R Dugas¹

Affiliations

¹ Department of Comparative Biomedical Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, Louisiana, 70803, USA.
² Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, 70112, USA.
³ Department of Biological Sciences, Louisiana State University A&M College and Pennington Biomedical Research Institute, Baton Rouge, Louisiana, 70803, USA.
⁴ Department of Chemistry, Louisiana State University A&M College, Baton Rouge, Louisiana, 70803, USA.
⁵ Department of Pathobiological Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, Louisiana, 70803, USA.

PMID: 38310335
DOI: 10.1093/toxsci/kfae007

No abstract available

Keywords: Air pollution; Alveolar type-II cells; Aryl hydrocarbon receptor; Cardiovascular health; Environmental toxicology; Environmentally persistent free radicals; Inhalation; Particulate matter.

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