Online mindfulness-based stress reduction improves anxiety and depression status and quality of life in caregivers of patients with severe mental disorders

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2024 Jan 31;53(1):108-115. doi: 10.3724/zdxbyxb-2023-0555.
[Article in English, Chinese]

Abstract

Objectives: To explore the effects of online mindfulness-based stress reduction (MBSR) on the anxiety and depression status, and quality of life in the caregivers of patients with severe mental disorders.

Methods: Ninety-three caregivers for patients with schizophrenia or bipolar disorder, who were hospitalized in Yunnan Provincial Mental Hospital in March 2021, were enrolled and randomly divided into control group (n=47) and MBSR intervention group (n=46). Both groups received basic health education and rehabilitation skill training, while the intervention group received additional online MBSR for 8 weeks. The anxiety and depression status, and the quality of life of the caregivers were evaluated by Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS) and the 36-item Short Form Health Survey (SF-36) before and 8 weeks after intervention, respectively.

Results: Thirteen caregivers dropped out of the study, and 80 subjects (40 in each group) were included in the final analysis. At the baseline, there were no significant differences in SAS, SDS and SF-36 scores between two groups (all P>0.05). Compared with the baseline, SAS and SDS scores in the intervention group significantly decreased after 8 weeks of intervention (both P<0.01) and were significantly lower than those in the control group (both P<0.01). There were no significant changes in the control group (all P>0.05). Except the physiological function dimension, the total score and the scores of each dimension of SF-36 in the intervention group were significantly increased after 8-week intervention (all P<0.05), and were significantly higher than those in the control group (all P<0.01). There were no significant changes in the control group before and after intervention (all P>0.05).

Conclusions: Online MBSR can reduce the anxiety and depression levels, improve the quality of life in the caregivers of patients with severe mental disorders.

目的: 探索网络正念减压疗法(MBSR)对严重精神障碍患者的照料者焦虑抑郁水平及生活质量的影响。方法: 纳入2021年3月在云南省精神病医院封闭病房住院治疗的、诊断为精神分裂症或双相情感障碍患者的照料者93名作为研究对象,使用随机数字表法随机分为两组:对照组47名和MBSR干预组46名。对照组给予健康宣教、康复技能训练,干预组在健康宣教、康复技能训练的基础上给予8周基于网络的MBSR。分别于基线及8周后采用焦虑自评量表(SAS)、抑郁自评量表(SDS)、SF-36健康量表(The 36-item Short Form Health Survey)进行效果评价。结果: 8周后,两组共脱落13名(对照组7名,干预组6名)。对照组与干预组基线SAS、SDS分值差异无统计学意义(均P >0.05)。8周后,干预组SAS、SDS分值较基线值均降低(均P<0.01),且明显低于对照组(均P <0.01),而对照组较基线值无明显变化(均P>0.05)。对照组与干预组基线SF-36总分及各个维度分值差异均无统计学意义(均P >0.05)。8周后,干预组SF-36总分及各个维度分值较基线时均升高,除生理功能维度外,差异均有统计学意义(均P<0.05),且明显高于对照组(均 P<0.01);而对照组较基线时无明显变化(均P>0.05)。结论: 网络MBSR可以减轻严重精神障碍患者照料者的焦虑抑郁水平,提高生活质量。.

Keywords: Anxiety; Caregiver of patients with severe mental illness; Depression; Mindfulness-based stress reduction; Quality of life; Web-based.

MeSH terms

  • Anxiety / therapy
  • Caregivers
  • China
  • Depression / therapy
  • Humans
  • Mental Disorders*
  • Mindfulness*
  • Quality of Life