Difficult to treat rheumatoid arthritis: Sequential therapy with different personalized biological targets could be an option

Affiliations

• ¹ Clinical Immunology Unit, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Catholic University of the Sacred Heart, Rome, Italy. Electronic address: elisa.gremese@unicatt.it.
• ² Clinical Immunology Unit, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Catholic University of the Sacred Heart, Rome, Italy.
• ³ Department of Rheumatology and Clinical Immunology, Department of Internal Medicine and Oncology, Semmelweis University, Budapest, Hungary; Heart and Vascular Center, Semmelweis University, Budapest, Hungary; Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Hospital of the Hospitaller Order of Saint John of God, Budapest, Hungary.
• ⁴ Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address: gianfranco.ferraccioli@unicatt.it.