Same-site transdifferentiation of basal cell carcinoma to squamous cell carcinoma as a mechanism of vismodegib treatment resistance: Two cases requiring multimodal and multidisciplinary limb-sparing techniques

Brooke A Burgess; Rebecca J Wang; Joshua L Owen

doi:10.1016/j.jdcr.2023.12.001

Same-site transdifferentiation of basal cell carcinoma to squamous cell carcinoma as a mechanism of vismodegib treatment resistance: Two cases requiring multimodal and multidisciplinary limb-sparing techniques

JAAD Case Rep. 2023 Dec 16:44:17-19. doi: 10.1016/j.jdcr.2023.12.001. eCollection 2024 Feb.

Authors

Brooke A Burgess¹, Rebecca J Wang², Joshua L Owen^{1

3}

Affiliations

¹ Division of Dermatology, University of Texas Health Science Center San Antonio, San Antonio, Texas.
² Long School of Medicine, University of Texas Health Science Center San Antonio, San Antonio, Texas.
³ Dermatology Service, South Texas Veterans Health Care System, San Antonio, Texas.

No abstract available

Keywords: basal cell carcinoma; intralesional 5-fluorouracil; limb sparing; same-site squamous cell carcinoma; secondary malignancy; transdifferentiation; vismodegib.